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Art. -Nr.: HY-121301

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Amperozide

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Based on 1 Customer Validation

Amperozide is an atypical antipsychotic that acts as an antagonist of the 5-HT2 receptor with a K_i value of 26 nM. Amperozide has a low affinity for D2 receptors.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 99.10%
CAS. Nr.: 75558-90-6
Formel: C₂₃H₂₉F₂N₃O
Molecular Weight:401.49

Speicherung:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Amperozide Chemical Structure

CAS. Nr.: 75558-90-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Amperozide is an atypical antipsychotic that acts as an antagonist of the 5-HT2 receptor with a K_i value of 26 nM. Amperozide has a low affinity for D2 receptors^[1].

IC₅₀ & Target

5-HT_2A Receptor

26 nM (Ki)

Alle 5-HT Receptor Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	95 μM Compound: Amperozide	Cytotoxicity activity against human HepG2 cells after 24 hrs Cytotoxicity activity against human HepG2 cells after 24 hrs	[PMID: 20547797]

Chemical Information

CAS. Nr. 75558-90-6
Appearance Solid
Molecular Weight 401.49
Formel C₂₃H₂₉F₂N₃O
Color White to off-white
SMILES

O=C(NCC)N1CCN(CC1)CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 125 mg/mL (311.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4907 mL

12.4536 mL

24.9072 mL

5 mM

0.4981 mL

2.4907 mL

4.9814 mL

10 mM

0.2491 mL

1.2454 mL

2.4907 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Meltzer HY, et al. Effect of amperozide on rat cortical 5-HT2 and striatal and limbic dopamine D2 receptor occupancy: implications for antipsychotic action. Eur J Pharmacol. 1992 May 27;216(1):67-71. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4907 mL	12.4536 mL	24.9072 mL	62.2681 mL
	5 mM	0.4981 mL	2.4907 mL	4.9814 mL	12.4536 mL
	10 mM	0.2491 mL	1.2454 mL	2.4907 mL	6.2268 mL
	15 mM	0.1660 mL	0.8302 mL	1.6605 mL	4.1512 mL
	20 mM	0.1245 mL	0.6227 mL	1.2454 mL	3.1134 mL
	25 mM	0.0996 mL	0.4981 mL	0.9963 mL	2.4907 mL
	30 mM	0.0830 mL	0.4151 mL	0.8302 mL	2.0756 mL
	40 mM	0.0623 mL	0.3113 mL	0.6227 mL	1.5567 mL
	50 mM	0.0498 mL	0.2491 mL	0.4981 mL	1.2454 mL
	60 mM	0.0415 mL	0.2076 mL	0.4151 mL	1.0378 mL
	80 mM	0.0311 mL	0.1557 mL	0.3113 mL	0.7784 mL
	100 mM	0.0249 mL	0.1245 mL	0.2491 mL	0.6227 mL

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
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Amperozide

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High-Throughput Bioactive Compound Library

Mass Spectrometry Human Metabolite Library

Lactylation Compound Library

Alle 5-HT Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Amperozide

GPCR/G Protein Compound Library

Neuronal Signaling Compound Library

Clinical Compound Library

Neurotransmitter Receptor Compound Library

Anti-Alzheimer's Disease Compound Library

Anti-Parkinson's Disease Compound Library

Neurodegenerative Disease-related Compound Library

5-HT Receptor Compound Library

Human Metabolite Library

Coagulation and Anti-coagulation Compound Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Clinical Compound Library Plus

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Mass Spectrometry Human Metabolite Library

Lactylation Compound Library

Alle 5-HT Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Amperozide Related Classifications

HY-121301 Related Classifications