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Art. -Nr.: HY-119996

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AR-C141990

1 Cited Publications

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AR-C141990 (Compound 30) is a potent blocker of the monocarboxylate transporter MCT1 with a K_i of 4.8 nM. AR-C141990 (Compound 30) inhibits CYP3A4 and CYP2C9 with IC₅₀ values of 16 μM.

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CAS. Nr.: 873327-59-4
Formel: C₂₆H₂₈N₄O₄S
Molecular Weight:492.59

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

AR-C141990 Chemical Structure

CAS. Nr.: 873327-59-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

AR-C141990 (Compound 30) is a potent blocker of the monocarboxylate transporter MCT1 with a K_i of 4.8 nM. AR-C141990 (Compound 30) inhibits CYP3A4 and CYP2C9 with IC₅₀ values of 16 μM^[1].

Alle Monocarboxylate Transporter Isoform-spezifische Produkte anzeigen :

Alle Cytochrome P450 Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 873327-59-4
Molecular Weight 492.59
Formel C₂₆H₂₈N₄O₄S
SMILES

O=C1N(CC(C)C)C2=C(C(C(N3C[C@H](O)CC3)=O)=C(CC4=CC=NC5=CC=CC=C45)S2)C(N1C)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Cell Death Differ

Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response. [Abstract]

2023 Sep;30(9):2104-2119. PMID: 37582865

Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Guile SD, et al. Potent blockers of the monocarboxylate transporter MCT1: novel immunomodulatory compounds. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2260-5. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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AR-C141990

1 Cited Publications

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Publications (1)
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AR-C141990

Publications Citing Use of MedChemExpress (MCE) AR-C141990

Alle Monocarboxylate Transporter Isoform-spezifische Produkte anzeigen

Alle Cytochrome P450 Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (1)

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

AR-C141990 Related Classifications

Art. -Nr.: HY-119996