Flucopride
Flucopride (Compound 4a) is an AChE inhibitor (IC50: 24 nM), and a partial 5-HT4R agonist (Ki: 9.6 nM for (h)5-HT4R). Flucopride promotes the non-amyloidogenic processing of APP in COS-7 transiently expressing (h)5-HT4R (EC50: 23.0 nM). Flucopride may has good gastrointestinal track (GIT) penetration, and blood-brain barrier (BBB) cross-membrane penetration (PAMPA assay).
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- CAS. Nr.: 1639925-34-0
- Formel: C22H33FN2O2
- Molecular Weight:376.51
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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AChE 24 nM (IC50) |
huamn 5-HT4(c) Receptor 9.6 nM (Ki) |
Chemical Information
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CAS. Nr. 1639925-34-0
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Molecular Weight 376.51
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Formel C22H33FN2O2
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SMILES
O=C(C1=CC(F)=C(N)C=C1OC)CCC2CCN(CC3CCCCC3)CC2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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