Indazole 1
Indazole 1 is a potent CDC2-like kinase 2 (CLK2) inhibitor (IC50=12.3 nM). Indazole 1 inhibits the phosphorylation of SR proteins (e.g., SRSF1, SRSF3) and modulates alternative splicing of Wnt signaling-related genes. Indazole 1 is promising for research of osteoarthritis.
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- CAS. Nr.: 2252153-37-8
- Formel: C19H24N4O
- Molecular Weight:324.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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CLK2 |
Chemical Information
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CAS. Nr. 2252153-37-8
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Molecular Weight 324.42
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Formel C19H24N4O
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SMILES
CC(C)C[C@H](N)COC1=CC(C2=CC3=C(NN=C3C)C=C2)=CN=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)