ONC1-13B
ONC1-13B is a potent androgen receptor (AR) antagonist with the activity of effectively inhibiting PSA expression in prostate cancer cells. ONC1-13B can effectively inhibit PSA expression and prostate cancer cell proliferation under DHT stimulation. ONC1-13B exerts its anti-tumor effect by preventing androgen from binding to AR and its nuclear translocation.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1351185-54-0
- Formel: C22H16F4N4O3S
- Molecular Weight:492.45
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| LNCaP | IC50 |
79.2 nM
Compound: (R)-6
|
Antiproliferative activity against human LNCAP cells after 3 days
Antiproliferative activity against human LNCAP cells after 3 days
|
[PMID: 26046313] |
Chemical Information
-
CAS. Nr. 1351185-54-0
-
Molecular Weight 492.45
-
Formel C22H16F4N4O3S
-
SMILES
O=C1[C@]2(CCOC2)N(C3=CC(F)=C(C=C3)C(NC)=O)C(N1C4=CC(C(F)(F)F)=C(C=C4)C#N)=S
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
ONC1-13B Related Classifications
HY-114246 Related Classifications
Powered by Bioz