BRD4 D1-IN-2
BRD4 D1-IN-2 (compound 26) is a potent and selective BRD4 D1 inhibitor (IC50<0.092 µM). BRD4 D1-IN-2 has 15 nM affinity against BRD4 D1 and over 500-fold selectivity against BRD2 D1 and BRD4 D2 via ITC.
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- CAS No.: 2863687-22-1
- Formule: C33H39F3N6O
- Masse moléculaire:592.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
BRD4 BD1 <0.092 μM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| A549 | EC50 |
3.6 μM
Compound: 26
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Cytotoxicity against human A549 cells assessed as viable cells incubated for 23 hrs by alamar blue assay
Cytotoxicity against human A549 cells assessed as viable cells incubated for 23 hrs by alamar blue assay
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[PMID: 35007061] |
Chemical Information
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CAS No. 2863687-22-1
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Masse moléculaire 592.70
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Formule C33H39F3N6O
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SMILES
CC(C1=CC=C(C(OC2=NC(C3=C(N=CN3C4CCN(CC4)CCN(C)C)C5=CC=C(C=C5)C(F)(F)F)=CC=N2)=C1)C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD4 D1-IN-2 Related Classifications
HY-142705 Related Classifications
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