BRD4 Inhibitor-19
BRD4 Inhibitor-19 is a BET inhibitor with an IC50 of 55 nM for BRD4-BD1. BRD4 Inhibitor-19 can be used for multiple myeloma research.
For research use only. We do not sell to patients.
- CAS No.: 2757865-63-5
- Formula: C29H25N5O3
- Molecular Weight:491.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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BD1 55 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CT26 | IC50 |
21.18 μM
Compound: 14
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Antiproliferative activity against human CT26 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Antiproliferative activity against human CT26 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 33862375] |
| HepG2 | IC50 |
19.49 μM
Compound: 14
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 33862375] |
| U-266 | IC50 |
3.45 μM
Compound: 14
|
Antiproliferative activity against human U-266 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Antiproliferative activity against human U-266 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 33862375] |
Chemical Information
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CAS No. 2757865-63-5
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Molecular Weight 491.54
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Formula C29H25N5O3
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SMILES
CC1=NOC(C)=C1C2=CC=C3C(C(N(C(N3C)=O)CC4=NN=C(O4)C5=CC=CC=C5)C6=CC=CC=C6)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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