BRD9 Degrader-4
BRD9 Degrader-4 is a bifunctional targeted degrader of the BRD9 protein, which promotes proteasomal degradation of BRD9 via a non-canonical PROTAC mechanism independent of the CRBN or VHL E3 ligases.
For research use only. We do not sell to patients.
- CAS No.: 3024541-39-4
- Formula: C30H40N4O4
- Molecular Weight:520.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
BRD9 |
In Vitro
BRD9 Degrader-4 (BRD9c) (24 h) exhibits potent BRD9 protein degradation activity in MV4-11 cells, with a DC50 ≤ 25 nM and Dmax ≥ 70 % determined by immunofluorescence Assay Protocol 2[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3024541-39-4
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Molecular Weight 520.66
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Formula C30H40N4O4
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SMILES
CC(C(C1=CC(OC)=C(C(OC)=C1)CN2CCN(CCC2)C(/C(C#N)=C/C(C)(C)C)=O)=CN3C)=C(C)C3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD9 Degrader-4 Related Classifications
HY-163811 Related Classifications
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