Cdc7-IN-12
Cdc7-IN-12 (compound 1) is a potent CDC7 inhibitor with an IC50 of <1 nM. Cdc7-IN-12 shows antiproliferative activities with IC50 of 100-1000 nM in COLO205 cells. Cdc7-IN-12 has the potential for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 2764865-33-8
- Formula: C16H14N2O2S
- Molecular Weight:298.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
Cdc7 <1 nM (IC50) |
Chemical Information
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CAS No. 2764865-33-8
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Molecular Weight 298.36
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Formula C16H14N2O2S
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SMILES
CC1=C2CCCOC3=C(SC(C(N1)=O)=C23)C4=CC=NC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cdc7-IN-12 Related Classifications
HY-143385 Related Classifications
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