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Maslinic acid

(Synonyms: Crategolic acid; 2α-Hydroxyoleanolic acid)
17 Cited Publications
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Based on 17 publication(s) in Google Scholar

Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.

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  • Pureté: 99.87%
  • CAS No.: 4373-41-5
  • Formule: C30H48O4
  • Masse moléculaire:472.70
  • Stockage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Maslinic acid Chemical Structure
    Maslinic acid Chemical Structure
  • Experimental Validation Results for Maslinic acid
  • Experimental Validation Results for Maslinic acid
  • Experimental Validation Results for Maslinic acid
  • Experimental Validation Results for Maslinic acid
  • Experimental Validation Results for Maslinic acid
  • Experimental Validation Results for Maslinic acid
CAS No.: 4373-41-5
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  • Maslinic acid Chemical Structure
    Maslinic acid Chemical Structure
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    Maslinic acid purchased from MedChemExpress. Usage Cited in: Fish Shellfish Immunol. 2025 Mar:158:110120. [Abstract]

    Customer Validation
     Maslinic acid (MA, 80 mg/L; 100 μL; i.p.) efficiently suppressed the transcription of Msp65. The mRNA levels of Msp65 were analyzed in the liver and spleen using qRT-PCR at different time points (6, 12, 24, 36, 48, 60 and 72 h post injection) after intraperitoneal injection with 80 mg/L MA.

  • 1/16

    Maslinic acid purchased from MedChemExpress. Usage Cited in: Fish Shellfish Immunol. 2025 Mar:158:110120. [Abstract]

    Customer Validation
     Survival curves of largemouth bass injected with different doses of Maslinic acid (MA, 5-640 mg/L; 100 μL; i.p.).

  • 1/16

    Maslinic acid purchased from MedChemExpress. Usage Cited in: Fish Shellfish Immunol. 2025 Mar:158:110120. [Abstract]

    Customer Validation
     Histological morphologies in the liver and spleen under Maslinic acid (MA, 80 mg/L; 100 μL; i.p.) treatment. Histological analysis revealed no pathological changes in the liver and spleen tissues of largemouth bass treated with 80 mg/L MA. Scale bars represented 50 μm.

  • 1/16

    Maslinic acid purchased from MedChemExpress. Usage Cited in: Cell Oncol (Dordr). 2022 Jun;45(3):367-379. [Abstract]

    Customer Validation
     WB analysis of phosphorylated and total NF-κB in IRAK2OE cells treated with 20 µM Maslinic acid (MA) for different times (0, 1, 2, 6, 12 and 24 h). Phosphorylated NF-κB was estimated by normalizing the band intensity of p-NF-κB against that of total NF-κB. The ratios below indicate the relative activity of treated cells compared with that of untreated cells from three independent experiments. The results showed that the level of phosphorylated NF-κB decreased in a time-dependent manner after treatment with MA.

  • 1/16

    Maslinic acid purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2021 Mar 1:500:228-243. [Abstract]

    Customer Validation
     Western blot analysis of GemR DT6066/MiaPaca2 cells treated with Maslinic acid (20 μM; 12 h) (NF-κB inhibitor) or placebo. The results showed that depletion of p65 by an inhibitor, Maslinic acid, significantly reduced p65 phosphorylation and its downstream B4GALT1 expression at protein levels in both mouse and human gemcitabine-resistant cells.

  • 1/16

    Maslinic acid purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2021 Mar 1:500:228-243. [Abstract]

    Customer Validation
     RT-PCR analysis of B4GALT1 mRNA expression in the GemR DT6066/MiaPaca2 cells treated with Maslinic acid (20 μM; 12 h) (NF-κB inhibitor) or placebo. The results showed that depletion of p65 by an inhibitor, Maslinic acid, significantly downregulated B4GALT1 expression at mRNA levels in both mouse and human gemcitabine-resistant cells.

  • Maslinic acid