CDK9-IN-36
CDK9-IN-36 (Compound T7) is a potent, selective and metabolically stable CDK9 inhibitor with an IC50 value of 1.2 nM. CDK9-IN-36 effectively suppresses cell proliferation, reduces colony formation, and induces apoptosis in Osimertinib (HY-15772)-resistant NSCLC cells by downregulating Mcl-1. CDK9-IN-36 also demonstrates antitumor efficacy in a tumor xenograft model.
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- Formule: C30H33F2N5O4
- Masse moléculaire:565.61
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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CDK9 1.2 nM (IC50) |
Chemical Information
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Masse moléculaire 565.61
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Formule C30H33F2N5O4
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SMILES
FC1=C(C2=CC(OCCCCCCO3)=C(C=C2)F)N=C(NC4=CC=C(C(NC5CCN(C(C)=O)CC5)=O)C3=C4)N=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK9-IN-36 Related Classifications
HY-173065 Related Classifications
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