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Imzokitug

(Synonyms: BMS-986340; CCR8.50)
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Imzokitug (BMS-986340; CCR8.50) is a CCR8 binding agent. Imzokitug inhibits tumor growth in syngeneic tumors by blocking CCR8 and depleting tumor-resident CCR8+ Treg cells, while increasing CD4+/CD8+ T cell proliferation and upregulating PD-1. Imzokitug can be used for cancer research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté : 98%
  • CAS No.: 2883771-61-5
  • Masse moléculaire:145.863 kDa
  • Stockage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Imzokitug
  • Experimental Validation Results for Imzokitug
  • Imzokitug Chemical Structure
    Imzokitug Chemical Structure
CAS No.: 2883771-61-5
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Imzokitug Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CCR8 (red) with Imzokitug (HY-P991001). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Imzokitug Chemical Structure
    1/16
  • Imzokitug
  • Flow Cytometry analysis of Raji cells labelling CCR8 (red) with Imzokitug (HY-P991001). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG1-kappa