LDN-0044878
LDN-0044878 is a PAK3 inhibitor. LDN-0044878 inhibits the proliferation or induces the death of p53-deficient cells. LDN-0044878 exhibits moderate trypanocidal activity against Trypanosoma brucei, but does not directly inhibit the core target Rhodesain. LDN-0044878 can be used in studies related to cervical adenocarcinoma and Trypanosoma brucei infection.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 296246-47-4
- Formule: C28H22N2OS
- Masse moléculaire:434.56
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Parasite
More
Activité biologique
Description
IC50 & Target
[1]|
PAK3 |
In Vitro
LDN-0044878 (75-150 h) reduces the viability of HeLa cells, with EC50 values of 10.7 μM (75 h), 15.5 μM (100 h) and 11.1 μM (150 h)[1].
LDN-0044878 (Compound 19) exhibits moderate trypanocidal activity, with an IC50 of 14.75 against T. brucei[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 296246-47-4
-
Masse moléculaire 434.56
-
Formule C28H22N2OS
-
SMILES
N1=C(NC(C2=CC=C(SC=3C=CC=CC3)C=C2)=C1C=4C=CC=CC4)C=5C=CC(OC)=CC5
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LDN-0044878 Related Classifications
HY-118606 Related Classifications
Powered by Bioz