PF-06745013
PF-06745013 (Compound 37) is a MAP4K4 inhibitor without time-dependent inhibition (TDI) risk of CYP3A4 (IC50 of 0.4 nM for MAP4K4). PF-06745013 has no accumulation CNS-impaired and non-ATP competitive activities in mouse models. PF-06745013 can be used for inflammatory diseases like diabetes and cancers research.
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- CAS No.: 2089334-01-8
- Formule: C21H19ClN2O3
- Masse moléculaire:382.84
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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MAP4K4 0.4 nM (IC50) |
Chemical Information
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CAS No. 2089334-01-8
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Masse moléculaire 382.84
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Formule C21H19ClN2O3
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SMILES
O=C(C(C)(C)OC1=CC=C(C2=CN=C(C(C3=CC=C(Cl)C=C3)=C2)N)C=C1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PF-06745013 Related Classifications
HY-123965 Related Classifications
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