Si5-N14
Si5-N14 is a key component of siloxane-incorporated lipid nanoparticles (SiLNP), possessing pro-vascular repair and anti-tumor activities. In the transgenic GFP mouse model, Si5-N14 can mediate CRISPR-Cas9 editing. In the Lewis lung carcinoma (LLC) tumor-bearing mouse model, Si5-N14 can knock out the expression of Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) to exert an anti-tumor effect. In a mouse model of lung injury induced by viral infection, the delivery of Fibroblast Growth Factor-2 (FGF-2) mRNA via Si5-N14 can promote vascular repair, increase blood oxygen levels, and improve lung function. Si5-N14 shows promise for research in the fields of oncology, pneumonia, and cardiovascular diseases.
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- CAS No.: 3006860-57-4
- Formule: C78H160N6O5Si2
- Masse moléculaire:1318.31
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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- Pureté et documentation
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Help & FAQs
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1,2-DLPC (Standard)Reference Standard
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Activité biologique
Description
IC50 & Target
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FGFR2 |
VEGFR2 |
Chemical Information
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CAS No. 3006860-57-4
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Masse moléculaire 1318.31
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Formule C78H160N6O5Si2
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SMILES
O=C(CCN(CCC[Si](C)(C)O[Si](C)(CCCN(CCC(NCCCCCCCCCCCCCC)=O)CCC(NCCCCCCCCCCCCCC)=O)C)CCC(NCCCCCCCCCCCCCC)=O)NCCCCCCCCCCCCCC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (263 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Si5-N14 Related Classifications
HY-165603 Related Classifications
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