country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-124585

Copy Link Print Information

Y08060

Y08060 is a selective BET inhibitor. Y08060 inhibits the viability of C4-2B and LNCaP cell lines with IC₅₀ values of 3.23 and 4.41 μM. Y08060 can suppress colony formation as well as AR expression in prostate cancer cell line. Y08060 can be studied in prostate cancer research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2222565-19-5
Formule: C₁₈H₁₉BrN₂O₆S
Masse moléculaire:471.32

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Y08060 Chemical Structure

CAS No.: 2222565-19-5

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Epigenetic Reader Domain :

Cellular Effect

Cell Line	Type	Value	Description	References
CWR22R	IC₅₀	3.38 μM Compound: 36	Antiproliferative activity against human 22Rv1 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay Antiproliferative activity against human 22Rv1 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay	[PMID: 29541371]
DU-145	IC₅₀	23.19 μM Compound: 36	Antiproliferative activity against human DU145 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay Antiproliferative activity against human DU145 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay	[PMID: 29541371]
LNCaP	IC₅₀	4.41 μM Compound: 36	Antiproliferative activity against human LNCAP cells after 96 hrs by Cell-Titer glo reagent based luminescence assay Antiproliferative activity against human LNCAP cells after 96 hrs by Cell-Titer glo reagent based luminescence assay	[PMID: 29541371]
LNCaP C4-2B	IC₅₀	3.23 μM Compound: 36	Antiproliferative activity against human C4-2B cells after 96 hrs by Cell-Titer glo reagent based luminescence assay Antiproliferative activity against human C4-2B cells after 96 hrs by Cell-Titer glo reagent based luminescence assay	[PMID: 29541371]
PC-3	IC₅₀	17.22 μM Compound: 36	Antiproliferative activity against human PC3 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay Antiproliferative activity against human PC3 cells after 96 hrs by Cell-Titer glo reagent based luminescence assay	[PMID: 29541371]

Chemical Information

CAS No. 2222565-19-5
Masse moléculaire 471.32
Formule C₁₈H₁₉BrN₂O₆S
SMILES

O=C1NC2=CC(OC)=C(NS(=O)(C3=CC(Br)=CC=C3OC)=O)C=C2OC1(C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xiang, Q., et al., (2018). Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer. ACS medicinal chemistry letters, 9(3), 262-267. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis

Amount: USD 0.00

Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Nom du produit:
CAS No.:
Species:
Pureté:
Quantité:

Y08060

Voir tous les produits spécifiques à Isoform Epigenetic Reader Domain

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Y08060 Related Classifications

HY-124585 Related Classifications