CB2 receptor agonist 8
CB2 receptor agonist 8 (Compound 17) is an agonist for cannabinoid receptor 2 (CB2 receptor). CB2 receptor agonist 8 exhibits cytotoxicity in cells U87, RPMI 8226, HL-60, and L929 with IC50s of 91.03, 16.29, 23.51 and 564.6 μM, respectively. CB2 receptor agonist 8 activates caspase 3/7, increases the expressions of pro-apoptotic genes BAX, BAD, BIM and tumor suppressor genes p53, and induces apoptosis in U87. CB2 receptor agonist 8 inhibits the migration of U87.
For research use only. We do not sell to patients.
- Formula: C23H26FN3O2
- Molecular Weight:395.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
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CB2R |
Chemical Information
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Molecular Weight 395.47
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Formula C23H26FN3O2
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SMILES
O=C(N[C@H](C(N)=O)C(C)(C)C)CC1=CN(CC2=CC=CC=C2)C3=CC=C(F)C=C31
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CB2 receptor agonist 8 Related Classifications
HY-168338 Related Classifications
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