SJFδ
SJFδ is a 10-atom linker PROTAC based on von Hippel-Lindau ligand. SJFδ degrades p38δ with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ.
(Pink: p38δ ligand (HY-45124); Blue: VHL ligand (HY-151227); Black: linker (HY-133143)).
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- CAS. Nr.: 2254609-23-7
- Formel: C62H63F2N7O12S
- Molecular Weight:1168.27
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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p38α 46.17 nM (DC50) |
VHL |
Chemical Information
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CAS. Nr. 2254609-23-7
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Molecular Weight 1168.27
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Formel C62H63F2N7O12S
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SMILES
FC1=CC=C(NC(C2(CC2)C(NC3=CC(F)=C(OC4=C(C=C(OC)C(OCCOCCOCCOC5=CC(C6=C(C)N=CS6)=CC=C5CNC([C@@H]7C[C@@H](O)CN7C([C@@H](N8C(C9=CC=CC=C9C8)=O)C(C)C)=O)=O)=C%10)C%10=NC=C4)C=C3)=O)=O)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SJFδ Related Classifications
HY-114405 Related Classifications
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