ABP688
Based on 1 Customer Validation
ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.02%
- CAS. Nr.: 924298-51-1
- Formel: C15H16N2O
- Molecular Weight:240.30
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Chemical Information
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Biologische Aktivität
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human mGluR5 1.7 nM (Ki) |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 924298-51-1
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Appearance Solid-Liquid Mixture
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Molecular Weight 240.30
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Formel C15H16N2O
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Color Light brown to brown
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SMILES
CC1=NC(C#CC2=C/C(CCC2)=N/OC)=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 83.33 mg/mL (346.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1615 mL | 20.8073 mL | 41.6146 mL | 104.0366 mL |
| 5 mM | 0.8323 mL | 4.1615 mL | 8.3229 mL | 20.8073 mL | |
| 10 mM | 0.4161 mL | 2.0807 mL | 4.1615 mL | 10.4037 mL | |
| 15 mM | 0.2774 mL | 1.3872 mL | 2.7743 mL | 6.9358 mL | |
| 20 mM | 0.2081 mL | 1.0404 mL | 2.0807 mL | 5.2018 mL | |
| 25 mM | 0.1665 mL | 0.8323 mL | 1.6646 mL | 4.1615 mL | |
| 30 mM | 0.1387 mL | 0.6936 mL | 1.3872 mL | 3.4679 mL | |
| 40 mM | 0.1040 mL | 0.5202 mL | 1.0404 mL | 2.6009 mL | |
| 50 mM | 0.0832 mL | 0.4161 mL | 0.8323 mL | 2.0807 mL | |
| 60 mM | 0.0694 mL | 0.3468 mL | 0.6936 mL | 1.7339 mL | |
| 80 mM | 0.0520 mL | 0.2601 mL | 0.5202 mL | 1.3005 mL | |
| 100 mM | 0.0416 mL | 0.2081 mL | 0.4161 mL | 1.0404 mL |
ABP688 Related Classifications
HY-110141 Related Classifications
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