CP 80080
CP 80080 is a Topoisomerase II ligand with almost no ability to stimulate topoisomerase II-mediated DNA cleavage. CP 80080 competes with DNA cleavage-enhancing antineoplastic agents for a common binding domain on Drosophila topoisomerase II, thereby attenuating the ability of these agents to stimulate topoisomerase II-mediated DNA cleavage. CP 80080 can be used in cancer-related research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 152247-02-4
- Formel: C20H16FNO4
- Molecular Weight:353.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Topoisomerase II |
Chemical Information
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CAS. Nr. 152247-02-4
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Molecular Weight 353.34
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Formel C20H16FNO4
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SMILES
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(C4=CC=C(OC)C=C4)=C3)C1=O)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Elsea SH, et al. Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugs. Biochemistry. 1997 Mar 11;36(10):2919-24. [Content Brief]
[2]. Osheroff N, et al. Defining functional drug-interaction domains on topoisomerase II by exploiting mechanistic differences between drug classes. Cancer chemotherapy and pharmacology. 1994;34 Suppl:S19-25. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CP 80080 Related Classifications
HY-124336 Related Classifications
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