Docarpamine
Docarpamine is an orally active dopamine prodrug that can be hydroxylated in the small intestine and liver to form active dopamine. Docarpamine mainly activates D1-like receptors in peripheral blood vessels to lower blood pressure and heart rate in a state of spontaneous hypertension. Docarpamine exerts a pressor and tachycardic effect by activating D1-like receptors, vasopressin V1 receptors, and α-adrenergic receptors in normal blood pressure conditions. Docarpamine can be used for research on renal vascular dilation and diuresis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 74639-40-0
- Formel: C21H30N2O8S
- Molecular Weight:470.54
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle Dopamine Receptor Isoform-spezifische Produkte anzeigen
MoreAlle Vasopressin Receptor Isoform-spezifische Produkte anzeigen
MoreAlle Adrenergic Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
D1 Receptor |
α adrenergic receptor |
Chemical Information
-
CAS. Nr. 74639-40-0
-
Molecular Weight 470.54
-
Formel C21H30N2O8S
-
SMILES
CCOC(OC1=C(C=C(C=C1)CCNC([C@@H](NC(C)=O)CCSC)=O)OC(OCC)=O)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Sanada H, et al. The effect of docarpamine, a dopamine pro-drug, on blood pressure and catecholamine levels in spontaneously hypertensive rats. Clin Exp Hypertens. 2000 May;22(4):419-29. [Content Brief]
[2]. Tsunoda T, et al. Treatment for ovarian hyperstimulation syndrome using an oral dopamine prodrug, docarpamine. Gynecol Endocrinol. 2003 Aug;17(4):281-6. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)