Go 7874
Go 7874 is a protein kinase C (PKC) inhibitor. Go 7874 mediated neuroprotection against LPS/IFNg-induced neuronal cell death in an immune-mediated neurotoxicity model, not through PKC activity. In contrast, the neuroprotective mechanism of Go 7874 involves inhibition of inducible nitric oxide synthase (iNOS) gene expression, followed by reduced nitric oxide (NO) production.
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- CAS. Nr.: 153207-86-4
- Formel: C27H26N4O4
- Molecular Weight:470.52
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 153207-86-4
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Molecular Weight 470.52
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Formel C27H26N4O4
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SMILES
O=C1NC(C2=C1C3=C(N(C4=C3C=C(C=C4)OC)CC(CN(C)C)O)C5=C2C6=C(C=CC=C6)N5C)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)