HDAC-IN-44
HDAC-IN-44 is a HDAC inhibitor with the IC50 value of 61.2 nM. HDAC-IN-44 shows high anticancer activity towards multiple cancer cell lines.
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- CAS. Nr.: 2414921-46-1
- Formel: C26H27BrN4O4
- Molecular Weight:539.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
HDAC-IN-44 (20 µg/mL; 24 h) treatment shows inhibitory effects on acute lymphoblastic leukemia (Molt 4 cells), T-cell lymphoblastic lymphoma (Sup-T1 cells), chronic myelogenous leukemia (K562 cells), gastric adenocarcinoma (AGS), prostate cancer (PC3 and LNCaP cells) and breast cancer (T47D cells) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Molt 4, Sup-T1, K562, AGS, PC-3, LNCaP, T47D cells[1]
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Concentration:20 µg/mL
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Incubation Time:24 hours
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Result:Exhibited IC50 values of 11, 9.1, 16.3, 7.1, 13.4, 32.7 and 9.2 μM in Molt 4, Sup-T1, K562, AGS, PC-3, LNCaP, T47D cells, respectively[1].
Chemical Information
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CAS. Nr. 2414921-46-1
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Molecular Weight 539.42
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Formel C26H27BrN4O4
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SMILES
O=C(NO)CCCCCN(C1)C([C@]2([H])CC3=C([C@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HDAC-IN-44 Related Classifications
HY-150500 Related Classifications
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