HDAC1-IN-8
HDAC1-IN-8 (compound 5c) is a potent and selective HDAC1 inhibitor with IC50 values of 11.94, 22.95, >500 µM for HDAC1, HDAC6, HDAC8, respectively. HDAC1-IN-8 shows antiproliferative activity. HDAC1-IN-8 induces cell cycle arrest at G1 and G2/M. HDAC1-IN-8 induces autophagy. HDAC1-IN-8 shows anticancer activity and has the potential for the research of lung cancer.
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- CAS. Nr.: 3066143-73-2
- Formel: C22H24N2O4
- Molecular Weight:380.44
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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HDAC1 11.94 μM (IC50) |
HDAC6 22.95 μM (IC50) |
HDAC8 >500 μM (IC50) |
Chemical Information
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CAS. Nr. 3066143-73-2
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Molecular Weight 380.44
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Formel C22H24N2O4
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SMILES
O=C(NO)CCCCCOC1=CC(C=C2)=C(C=C1)N=C2C3=CC=C(OC)C=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HDAC1-IN-8 Related Classifications
HY-168477 Related Classifications
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