Pulixin
Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.
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- CAS. Nr.: 2826264-81-5
- Formel: C14H11NO4
- Molecular Weight:257.24
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Plasmodium |
Microbial Metabolite |
In Vitro
Pulixin, a fungal metabolite, inhibits Plasmodium falciparum transmission and infection. It does not show cytotoxic effects at a concentration of 116 µM or lower[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2826264-81-5
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Molecular Weight 257.24
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Formel C14H11NO4
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SMILES
O=C1C2=C(O)C=C(O)C=C2C3=C(O1)C=C(N)C=C3C
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Structure Classification
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Initial Source
Purpureocillium lilacinum
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Pulixin Related Classifications
HY-N10197 Related Classifications
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