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Art. -Nr.: HY-111402

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Pyridomycin

(Synonyms: Erizomycin; NSC 246134)

Pyridomycin (Erizomycin) is a selective and low cytotoxic inhibitor of Mycobacterium tuberculosis that effectively targets InhA. Pyrdomycin is also an antibiotic that can be obtained from metabolites of Dactylosporangium fulvum. Pyrdomycin can be used in the study of bacterial infections such as tuberculosis.

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CAS. Nr.: 18791-21-4
Formel: C₂₇H₃₂N₄O₈
Molecular Weight:540.56

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Pyridomycin Chemical Structure

CAS. Nr.: 18791-21-4

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Biologische Aktivität
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- In Vitro
Chemical Information
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Biologische Aktivität

Beschreibung

Alle Antibiotic Isoform-spezifische Produkte anzeigen :

In Vitro

Pyridomycin shows good inhibitory activity against Mycobacterium tuberculosis (minimum inhibitory concentration=0.39 µg/mL)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 18791-21-4
Molecular Weight 540.56
Formel C₂₇H₃₂N₄O₈
SMILES

O=C(C1=NC=CC=C1O)N[C@H](C(N[C@@H](CC2=CC=CN=C2)[C@@H](O)[C@H]3C)=O)[C@@H](C)OC(/C(OC3=O)=C(C)/CC)=O
Synonyms

Erizomycin; NSC 246134
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Hartkoorn RC, et al. Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med. 2012 Oct;4(10):1032-42. [Content Brief]

[2]. Hartkoorn RC, et al. Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA. Nat Chem Biol. 2014 Feb;10(2):96-8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Pyridomycin

Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19)

Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5)

Acetyl-6-formylpterin

Neospiramycin I

25-Desacetyl rifampicin

Enopeptin A

Aranciamycin A

Amycolatopsin A

Alle Antibiotic Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Bioz

Pyridomycin

Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19)

Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5)

Acetyl-6-formylpterin

Neospiramycin I

25-Desacetyl rifampicin

Enopeptin A

Aranciamycin A

Amycolatopsin A

Alle Antibiotic Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Pyridomycin Related Classifications

HY-111402 Related Classifications

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