(S,S)-R116010
(S,S)-R116010 is a (S,S)-enantiomer of R116010 (HY-121500A). R116010 is a retinoic acid (RA) metabolism inhibitor and can inhibit hydroxylase CYP26. (S,S)-R116010 shows antitumor effects.
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- CAS. Nr.: 355860-40-1
- Formel: C21H23N5S
- Molecular Weight:377.51
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
CYP26 |
Chemical Information
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CAS. Nr. 355860-40-1
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Molecular Weight 377.51
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Formel C21H23N5S
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SMILES
C[C@H](N(C)C)[C@H](C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4C=CN=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Wu W, et al. Enantioselective and Diastereoselective Construction of Chiral Amino Alcohols by Iridium-f-Amphox-Catalyzed Asymmetric Hydrogenation via Dynamic Kinetic Resolution. Org Lett. 2017 May 19;19(10):2548-2551. [Content Brief]
[2]. Armstrong JL, et al. Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells. Br J Cancer. 2005 Feb 28;92(4):696-704. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(S,S)-R116010 Related Classifications
HY-121500 Related Classifications
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