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Art. -Nr.: HY-106371

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Siccanin

Siccanin is a succinate dehydrogenase (SDH) inhibitor (IC₅₀=0.9 μM) with species-selective activity. Siccanin also is a antibiotic against pathogenic fungi.

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CAS. Nr.: 22733-60-4
Formel: C₂₂H₃₀O₃
Molecular Weight:342.47

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Siccanin Chemical Structure

CAS. Nr.: 22733-60-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Siccanin is a succinate dehydrogenase (SDH) inhibitor (IC₅₀=0.9 μM) with species-selective activity. Siccanin also is a antibiotic against pathogenic fungi^[1].

IC₅₀ & Target

Succinate Dehydrogenase Inhibitor

Alle Antibiotic Isoform-spezifische Produkte anzeigen :

In Vitro

Siccanin (10 μg/mL) is species-selective, and Siccanin inhibits bacterial SDH from P. aeruginosa and P. putida but not SDH from E. coli, and C. glutamicum; Siccanin inhibits rodent SDH but not porcine SDH^[1].
Specifically, Siccanin inhibits SDH from P. aeruginosa (residual activity 13%) and P. putida (>1%) membranes, and of mouse (>7%) and rat (19%) liver mitochondria, but not SDH from E. coli (77%) and C. glutamicum (97%) membranes and of porcine heart mitochondria (106%)^[1].
Siccanin (3 μg/mL) competely inhibits the growth of Trichophyton mentagrophytes (IC₅₀=0.3 μg/mL)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 22733-60-4
Molecular Weight 342.47
Formel C₂₂H₃₀O₃
SMILES

C[C@@]12[C@@]3([H])[C@@]4(CO[C@@]3([H])C5=C(O)C=C(C)C=C5O2)[C@@](C(C)(CCC4)C)([H])CC1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Mogi T, et al. Siccanin rediscovered as a species-selective succinate dehydrogenase inhibitor. J Biochem. 2009 Sep;146(3):383-7. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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Siccanin

Alle Antibiotic Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Siccanin Related Classifications

HY-106371 Related Classifications