MCPG sodium
MCPG is a carboxylic phenyl glycine. MCPG can block metabotropic glutamate receptor (mGluR)(HY-15129) and has antagonistic activity of mGluR subtype. MCPG can be used to study the induction and maintenance of long-term potentiation (LTP) .
For research use only. We do not sell to patients.
- CAS No.: 1303994-09-3
- Formula: C10H10NNaO4
- Molecular Weight:231.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
MCPG (300 μM, 1, and 3 mM) inhibits the concentration-dependent increase of phosphoinositol (PPI) hydrolysis induced by 1S, 3R-aminocyclopentane-1, 3-dicarboxic acid (ACPD) in hippocampus sections [1].
MCPG (20 mM, 200 mM) has a selective blocking effect on long-term potentiation (LTP) (20 mM), and also inhibits tetanus-induced short-term potentiation (STP) (200 mM) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1303994-09-3
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Molecular Weight 231.18
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Formula C10H10NNaO4
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SMILES
O=C(O[Na])C(C)(N)C1=CC=C(C(O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)