Docarpamine
Docarpamine is an orally active dopamine prodrug that can be hydroxylated in the small intestine and liver to form active dopamine. Docarpamine mainly activates D1-like receptors in peripheral blood vessels to lower blood pressure and heart rate in a state of spontaneous hypertension. Docarpamine exerts a pressor and tachycardic effect by activating D1-like receptors, vasopressin V1 receptors, and α-adrenergic receptors in normal blood pressure conditions. Docarpamine can be used for research on renal vascular dilation and diuresis.
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- CAS No.: 74639-40-0
- Formule: C21H30N2O8S
- Masse moléculaire:470.54
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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D1 Receptor |
α adrenergic receptor |
Chemical Information
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CAS No. 74639-40-0
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Masse moléculaire 470.54
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Formule C21H30N2O8S
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SMILES
CCOC(OC1=C(C=C(C=C1)CCNC([C@@H](NC(C)=O)CCSC)=O)OC(OCC)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Sanada H, et al. The effect of docarpamine, a dopamine pro-drug, on blood pressure and catecholamine levels in spontaneously hypertensive rats. Clin Exp Hypertens. 2000 May;22(4):419-29. [Content Brief]
[2]. Tsunoda T, et al. Treatment for ovarian hyperstimulation syndrome using an oral dopamine prodrug, docarpamine. Gynecol Endocrinol. 2003 Aug;17(4):281-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)