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Cat. No.: HY-N14247

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Exfoliazone

Exfoliazone is a phenoxazine antibiotic. Exfoliazone has the activity of resisting Valsa ceratosperma, and the ED₅₀ that inhibits mycelial growth is 70 μg/mL.

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CAS No.: 132627-73-7
Formule: C₁₅H₁₂N₂O₄
Masse moléculaire:284.27

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Exfoliazone Chemical Structure

CAS No.: 132627-73-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Protocole (1)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Exfoliazone is a phenoxazine antibiotic. Exfoliazone has the activity of resisting Valsa ceratosperma, and the ED₅₀ that inhibits mycelial growth is 70 μg/mL^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	2.52 μM Compound: 8	Cytotoxicity against human A2780 cells by MTT method Cytotoxicity against human A2780 cells by MTT method	[PMID: 23164710]
A549	IC₅₀	9.16 μM Compound: 8	Cytotoxicity against human A549 cells by MTT method Cytotoxicity against human A549 cells by MTT method	[PMID: 23164710]
BGC-823	IC₅₀	3.4 μM Compound: 8	Cytotoxicity against human BGC823 cells by MTT method Cytotoxicity against human BGC823 cells by MTT method	[PMID: 23164710]
HCT-8	IC₅₀	4.89 μM Compound: 8	Cytotoxicity against human HCT8 cells by MTT method Cytotoxicity against human HCT8 cells by MTT method	[PMID: 23164710]

Chemical Information

CAS No. 132627-73-7
Masse moléculaire 284.27
Formule C₁₅H₁₂N₂O₄
SMILES

O=C1C=C2OC3=CC=C(CO)C=C3N=C2C=C1NC(C)=O
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Cell Biology

Filamentous Fungal Mold Culture and Sporulation
Filamentous fungal mold culture and sporulation assays grow hyphae under defined nutritional and environmental conditions until asexual spores, commonly conidia, are produced; the main readouts are colony growth, sporulation onset, conidial yield, conidial morphology, viability, and, when relevant, downstream infectivity or stress phenotype.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Feng-Xian Yang, et al. New phenoxazinone-related alkaloids from strain Streptomyces sp. KIB-H1318. J Antibiot (Tokyo). 2018 Nov;71(12):1040-1043. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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