NYLTHRQ
NYLTHRQ is a peptide. NYLTHRQ specifically blocks the interaction between sVEGFR1-i13 and β1 integrin, and inhibits the activation of VEGFR1 and VEGFR2. NYLTHRQ inhibits cancer cell proliferation. NYLTHRQ can be used in the research of tumors such as lung squamous cell carcinoma.
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- CAS No.: 1004284-41-6
- Formule: C40H62N14O12
- Masse moléculaire:931.01
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
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VEGFR1 |
VEGFR2 |
NYLTHRQ (10 μg/mL; 72 h) specifically blocks the interaction between sVEGFR1-i13 and β1 integrin in MGH7 cells, inhibits VEGFR activation, and reduces cell proliferation activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MGH7 squamous cell lung carcinoma (SQLC) cells
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Concentration:10 μg/mL
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Incubation Time:72 h
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Result:Prevented the activation of VEGFR1 (Tyr1213) and VEGFR2 (Tyr1214) proteins.
Blocked the increased cell proliferation induced by sVEGFR1-i13-containing conditioned supernatants.
Chemical Information
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CAS No. 1004284-41-6
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Masse moléculaire 931.01
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Formule C40H62N14O12
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Sequence
Asn-Tyr-Leu-Thr-His-Arg-Gln
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Sequence Shortening
NYLTHRQ
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NYLTHRQ Related Classifications
HY-P11649 Related Classifications
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