Pentixafor peptide cyclo(dTyr-dOrn(NMe)-R-Nal-G)
Pentixafor peptide cyclo(dTyr-dOrn(NMe)-R-Nal-G) is a peptide that targets CXCR4. Pentixafor peptide cyclo(dTyr-dOrn(NMe)-R-Nal-G) constitutes the peptide moiety of Pentixafor (HY-153549). Pentixafor is a highly selective cyclic pentapeptide ligand targeting the CXCR4 receptor and is suitable for research into radionuclide-drug conjugates (RDCs).
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- CAS No.: 1339959-27-1
- Formule: C36H47N9O6
- Masse moléculaire:701.82
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Voir tous les produits spécifiques à Isoform Radionuclide-Drug Conjugates (RDCs)
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Activité biologique
Description
IC50 & Target
[1]|
CXCR4 |
RDC Peptide |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
6 nM
Compound: 7
|
Displacement of [125I]-CPCR4 from CXCR4 receptor in human Jurkat cells after 2 hrs by gamma counting
Displacement of [125I]-CPCR4 from CXCR4 receptor in human Jurkat cells after 2 hrs by gamma counting
|
[PMID: 21905730] |
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1339959-27-1
-
Masse moléculaire 701.82
-
Formule C36H47N9O6
-
Sequence
Cyclo(dTyr-dOrn(NMe)-Arg-Nal-Gly)
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Sequence Shortening
Cyclo(dTyr-dOrn(NMe)-R-Nal-G)
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)