PRMT5-IN-45
PRMT5-IN-45 (compound 36) is a potent and selective PRMT5 inhibitor with an IC50 of 3 nM. PRMT5-IN-45 potently reduces the level of symmetric dimethylarginines (sDMA) and inhibits the proliferation of MOLM-13 cell lines by inducing apoptosis and cell cycle arrest.
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- Formule: C26H31N7O2
- Masse moléculaire:473.57
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Voir tous les produits spécifiques à Isoform Histone Methyltransferase
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Activité biologique
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PRMT5 3 nM (IC50) |
Chemical Information
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Masse moléculaire 473.57
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Formule C26H31N7O2
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SMILES
O[C@@H]1[C@H](O)[C@@H](CCC2=CC=C3C=CC(N)=NC3=C2)C[C@H]1N4C=CC5=C(N6CCNCC6)N=CN=C54
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)