SL010110
SL010110 is an anti-hyperglycemic agent. SL010110 potently inhibits gluconeogenesis by inhibiting SIRT2, activating p300, and subsequently promoting PEPCK1 degradation. SL010110 downregulates the protein level of PEPCK1 without affecting the gene expressions of PEPCK, glucose-6-phosphatase, and fructose-1,6-bisphosphatase. SL010110 significantly improves glucose homeostasis in type 2 diabetic (T2D) mice model. SL010110 can be used for T2D research.
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- CAS No.: 380173-90-0
- Formule: C16H16O5
- Masse moléculaire:288.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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SIRT2 |
p300 |
Chemical Information
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CAS No. 380173-90-0
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Masse moléculaire 288.30
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Formule C16H16O5
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SMILES
C=CCC1=CC(=C(C=C1)OCC2=CC=C(C(=O)O)O2)OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SL010110 Related Classifications
HY-W197205 Related Classifications
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