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Cat. No.: HY-167686

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Variabilin

(Synonyms: Homopisatin)

Variabilin (Homopisatin) is a potent RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermacentor variabilis. Variabilin potently inhibits platelet aggregation induced by the platelet agonists ADP, collagen, and thrombin receptor peptide SFLLRNP. Variabilin also blocks platelet adhesion to immobilized Fg. In addition, Variabilin inhibits binding of purified human GPIIb-IIIa to immobilized Fg.

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CAS No.: 3187-52-8
Formule: C₁₇H₁₆O₅
Masse moléculaire:300.31

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Variabilin Chemical Structure

CAS No.: 3187-52-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

CAS No. 3187-52-8
Masse moléculaire 300.31
Formule C₁₇H₁₆O₅
SMILES

O[C@@]12[C@@](OC3=CC(OC)=CC=C32)([H])C4=CC=C(OC)C=C4OC1
Synonyms

Homopisatin
Structure Classification
- Others
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wang X, et al. Variabilin, a novel RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermacentor variabilis. J Biol Chem. 1996 Jul 26;271(30):17785-90. [Content Brief]

[2]. Kurosawa K, et al. Variabilin, a 6a-hydroxypterocarpan from Dalbergia variabilis[J]. Phytochemistry, 1978, 17(8): 1417-1418.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Variabilin

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Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Variabilin Related Classifications

HY-167686 Related Classifications