Y02224
Y02224 is a potent BRD4 inhibitor and exhibits reasonable antiproliferative effect on leukemia cells.Y02224 has the potential for? CRPC research.
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- CAS No.: 1853988-48-3
- Formule: C20H17BrN2O4S
- Masse moléculaire:461.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
IC50: BRD4[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
2.99 μM
Compound: 85
|
Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay
|
[PMID: 26731490] |
| HT-29 | IC50 |
12.9 μM
Compound: 85
|
Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay
|
[PMID: 26731490] |
| MV4-11 | IC50 |
1.3 μM
Compound: 85
|
Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay
|
[PMID: 26731490] |
Chemical Information
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CAS No. 1853988-48-3
-
Masse moléculaire 461.33
-
Formule C20H17BrN2O4S
-
SMILES
O=C1C2=C(C3=CC=C2)C(N1CC)=CC=C3NS(C4=C(C=CC(Br)=C4)OC)(=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)