ZEN-3862
Based on 1 Customer Validation
ZEN-3862 is a BET inhibitor with IC50s of 0.16 and 0.13 μM for BRD4(BD1) and BRD4(BD2) , respectively. ZEN-3862 can be used to form PROTACs to induce degradation of BRD4.
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- Pureté : 95.27%
- CAS No.: 1952264-33-3
- Formule: C19H17FN2O3
- Masse moléculaire:340.35
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
BRD4 (BD1) 0.16 μM (IC50) |
BRD4 (BD2) 0.13 μM (IC50) |
Chemical Information
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CAS No. 1952264-33-3
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Appearance Solid
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Masse moléculaire 340.35
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Formule C19H17FN2O3
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Color White to off-white
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SMILES
O=C(C=CC(C1=C(C)ON=C1C)=C2)N2CC3=CC(F)=C(C4OC4)C=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 83.33 mg/mL (244.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9382 mL | 14.6908 mL | 29.3815 mL | 73.4538 mL |
| 5 mM | 0.5876 mL | 2.9382 mL | 5.8763 mL | 14.6908 mL | |
| 10 mM | 0.2938 mL | 1.4691 mL | 2.9382 mL | 7.3454 mL | |
| 15 mM | 0.1959 mL | 0.9794 mL | 1.9588 mL | 4.8969 mL | |
| 20 mM | 0.1469 mL | 0.7345 mL | 1.4691 mL | 3.6727 mL | |
| 25 mM | 0.1175 mL | 0.5876 mL | 1.1753 mL | 2.9382 mL | |
| 30 mM | 0.0979 mL | 0.4897 mL | 0.9794 mL | 2.4485 mL | |
| 40 mM | 0.0735 mL | 0.3673 mL | 0.7345 mL | 1.8363 mL | |
| 50 mM | 0.0588 mL | 0.2938 mL | 0.5876 mL | 1.4691 mL | |
| 60 mM | 0.0490 mL | 0.2448 mL | 0.4897 mL | 1.2242 mL | |
| 80 mM | 0.0367 mL | 0.1836 mL | 0.3673 mL | 0.9182 mL | |
| 100 mM | 0.0294 mL | 0.1469 mL | 0.2938 mL | 0.7345 mL |
ZEN-3862 Related Classifications
HY-111978 Related Classifications
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