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Art. -Nr.: HY-W777120

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Cisapride-_{13_{C_,d₃}}

(Synonyms: R 51619-13C,d3; (±)-Cisaprid-_{13_{C_,d₃}})

Cisapride-¹³C,d₃ (R 51619-¹³C,d₃) is the deuteriumand ¹³C-labeled Cisapride (HY-14149). Cisapride (R 51619) is an orally active 5-HT4 receptor agonist with an EC₅₀ value of 140 nM. Cisapride is a hERG blocker with an IC₅₀ value of 9.4 nM. Cisapride is a gastroprokinetic agent that stimulates gastrointestinal motor activity.

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CAS. Nr.: 1285970-69-5
Formel: C₂₂¹³CH₂₆D₃ClFN₃O₄
Molecular Weight:469.96

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (241 KB)

Cisapride-_{13_{C_{,d_{3_{Chemical Structure}}}}}

CAS. Nr.: 1285970-69-5

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Biologische Aktivität
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Biologische Aktivität

Beschreibung

Alle 5-HT Receptor Isoform-spezifische Produkte anzeigen :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS. Nr. 1285970-69-5
Unlabeled Cas 81098-60-4
Molecular Weight 469.96
Formel C₂₂¹³CH₂₆D₃ClFN₃O₄
SMILES

FC1=CC=C(OCCCN2C[C@H](OC)[C@H](NC(C3=C(O[13C]([2H])([2H])[2H])C=C(N)C(Cl)=C3)=O)CC2)C=C1
Synonyms

R 51619-13C,d3; (±)-Cisaprid-_{13_{C_,d₃}}
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.