1. GPCR/G Protein Neuronal Signaling
  2. 5-HT Receptor
  3. Clothiapine

Clothiapine, an atypical antipsychotic agent, shares with clozapine its strong antiserotonergic properties.

For research use only. We do not sell to patients.

Clothiapine Chemical Structure

Clothiapine Chemical Structure

CAS No. : 2058-52-8

Size Price Stock Quantity
5 mg USD 160 In-stock
10 mg USD 260 In-stock
25 mg USD 520 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Clothiapine, an atypical antipsychotic agent, shares with clozapine its strong antiserotonergic properties[1].

Molecular Weight

343.87

Formula

C18H18ClN3S

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CN1CCN(CC1)C2=NC3=CC=CC=C3SC4=CC=C(C=C24)Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (181.75 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9081 mL 14.5404 mL 29.0808 mL
5 mM 0.5816 mL 2.9081 mL 5.8162 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.93%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9081 mL 14.5404 mL 29.0808 mL 72.7019 mL
5 mM 0.5816 mL 2.9081 mL 5.8162 mL 14.5404 mL
10 mM 0.2908 mL 1.4540 mL 2.9081 mL 7.2702 mL
15 mM 0.1939 mL 0.9694 mL 1.9387 mL 4.8468 mL
20 mM 0.1454 mL 0.7270 mL 1.4540 mL 3.6351 mL
25 mM 0.1163 mL 0.5816 mL 1.1632 mL 2.9081 mL
30 mM 0.0969 mL 0.4847 mL 0.9694 mL 2.4234 mL
40 mM 0.0727 mL 0.3635 mL 0.7270 mL 1.8175 mL
50 mM 0.0582 mL 0.2908 mL 0.5816 mL 1.4540 mL
60 mM 0.0485 mL 0.2423 mL 0.4847 mL 1.2117 mL
80 mM 0.0364 mL 0.1818 mL 0.3635 mL 0.9088 mL
100 mM 0.0291 mL 0.1454 mL 0.2908 mL 0.7270 mL
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Clothiapine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Clothiapine
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HY-117083
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