1. Neuronal Signaling
    Metabolic Enzyme/Protease
  2. AChE
    Endogenous Metabolite
  3. Coumaran

Coumaran (Synonyms: 2,3-Dihydrobenzofuran)

Cat. No.: HY-75247 Purity: 99.69%
Handling Instructions

Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran can be used as a biopesticide.

For research use only. We do not sell to patients.

Coumaran Chemical Structure

Coumaran Chemical Structure

CAS No. : 496-16-2

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran can be used as a biopesticide[1].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

120.15

Formula

C₈H₈O

CAS No.

496-16-2

SMILES

C12=CC=CC=C1CCO2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 150 mg/mL (1248.44 mM; Need ultrasonic)

DMSO : 150 mg/mL (1248.44 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.3229 mL 41.6146 mL 83.2293 mL
5 mM 1.6646 mL 8.3229 mL 16.6459 mL
10 mM 0.8323 mL 4.1615 mL 8.3229 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 3.75 mg/mL (31.21 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3.75 mg/mL (31.21 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3.75 mg/mL (31.21 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Coumaran2,3-DihydrobenzofuranAChEEndogenous MetaboliteAcetylcholinesteraseacetylcholinesterasebiopesticideInhibitorinhibitorinhibit

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Coumaran
Cat. No.:
HY-75247
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