2. Protein Tyrosine Kinase/RTK Autophagy Apoptosis
  3. Bcr-Abl Src Autophagy Apoptosis
  4. DA5-HTL

DA5-HTL is a compound combined dasatinib with HaloTag system efficiently inhibits the growth of the cancer cells with GI50 of 1.923 nM.

For research use only. We do not sell to patients.

DA5-HTL

DA5-HTL Chemical Structure

CAS No. : 3110091-19-2

Size Price Stock Quantity
Oil + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Oil
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

DA5-HTL Related Antibodies

Top Publications Citing Use of Products

View All Bcr-Abl Isoform Specific Products:

View All Isoforms
Abl Bcr-Abl

View All Src Isoform Specific Products:

View All Isoforms
Lck Fyn Blk Fgr Hck Lyn Yes SRC-3

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

DA5-HTL is a compound combined dasatinib with HaloTag system efficiently inhibits the growth of the cancer cells with GI50 of 1.923 nM[1].

Molecular Weight

869.90

Formula

C39H58Cl2N8O8S
CAS No.
Appearance

Oil

SMILES

CC1=C(C(Cl)=CC=C1)NC(C2=CN=C(S2)NC3=CC(N4CCN(CC4)CCOC(NCCOCCOCCOCCOCCOCCCCCCCl)=O)=NC(C)=N3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (28.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1496 mL 5.7478 mL 11.4956 mL
5 mM 0.2299 mL 1.1496 mL 2.2991 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1496 mL 5.7478 mL 11.4956 mL 28.7389 mL
5 mM 0.2299 mL 1.1496 mL 2.2991 mL 5.7478 mL
10 mM 0.1150 mL 0.5748 mL 1.1496 mL 2.8739 mL
15 mM 0.0766 mL 0.3832 mL 0.7664 mL 1.9159 mL
20 mM 0.0575 mL 0.2874 mL 0.5748 mL 1.4369 mL
25 mM 0.0460 mL 0.2299 mL 0.4598 mL 1.1496 mL
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DA5-HTL Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DA5-HTL3110091-19-2Bcr-AblSrcAutophagyApoptosisdasatinibHaloTag systemInhibitorinhibitorinhibit

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