2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. (E)-[10]-Shogaol

(E)-[10]-Shogaol is a 5-HT1A receptor partial agonist found in Zingiber officinale, with a Ki of 5.84 μM. (E)-[10]-Shogaol may be used in research on anxiety and depression.

For research use only. We do not sell to patients.

(E)-[10]-Shogaol

(E)-[10]-Shogaol Chemical Structure

CAS No. : 104186-05-2

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Other Forms of (E)-[10]-Shogaol:

(E)-[10]-Shogaol Related Antibodies

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Description

(E)-[10]-Shogaol is a 5-HT1A receptor partial agonist found in Zingiber officinale, with a Ki of 5.84 μM. (E)-[10]-Shogaol may be used in research on anxiety and depression[1].

IC50 & Target

5-HT1A Receptor

5.84 μM (Ki)

In Vitro

(E)-[10]-Shogaol exhibits a Ki of 5.84 μM against 5-HT1A in HEK293 cells[1].
(E)-[10]-Shogaol (10 μM) increases [35S]-GTPγS binding[1].
(E)-[10]-Shogaol crosses the Caco-2 monolayer by slow passive diffusion[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(E)-[10]-Shogaol Related Antibodies
Molecular Weight

332.48

Formula

C21H32O3
CAS No.
SMILES

CCCCCCCCC/C=C/C(CCC1=CC(OC)=C(C=C1)O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(E)-[10]-Shogaol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E)-[10]-Shogaol104186-05-25-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptor5-HT1A receptorZingiber officinaleanxietydepressionInhibitorinhibitorinhibit

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