Ganglioside GT1b (porcine) ammonium
Based on 1 Customer Validation
Ganglioside GT1b (porcine) ammonium is a member of the ganglioside family. Ganglioside GT1b (porcine) ammonium acts as a protective signal against nerve injury-induced spinal synapse elimination. Ganglioside GT1b (porcine) ammonium induces HA synthesis and the phosphorylation of Akt/mTOR in orbital fibroblasts. Ganglioside GT1b (porcine) ammonium enhances porcine oocyte maturation and induces activation of EGFR and ERK1/2 signaling. Ganglioside GT1b (porcine) ammonium is a putative host cell receptor for the Merkel cell polyomavirus. Ganglioside GT1b (porcine) ammonium can be used for the researches of cancer, infection, immunology, endocrinology and neurological disease, such as Thyroid eye disease.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 59247-13-1
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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HY-131686
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Biological Activity
Description
Chemical Information
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CAS No. 59247-13-1
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Appearance Solid
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Color White to off-white
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SMILES
O[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[Ceramide])CO)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O[C@]5(C(O)=O)C[C@@H]([C@H]([C@@H](O5)[C@H](O)[C@H](O)CO)NC(C)=O)O)O)O)CO)O[C@]6(C(O)=O)C[C@@H]([C@H]([C@@H](O6)[C@H](O)[C@H](O[C@]7(C(O)=O)C[C@@H]([C@H]([C@@H](O7)[C@H](O)[C@H](O)CO)NC(C)=O)O)CO)NC(C)=O)O)O)O.N.N.N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Lee J, et al. Ganglioside GT1b prevents selective spinal synapse removal following peripheral nerve injury. EMBO Rep. 2025 Jun;26(12):2994-3023. [Content Brief]
[2]. Yoo HK, et al. Ganglioside GT1b increases hyaluronic acid synthase 2 via PI3K activation with TLR2 dependence in orbital fibroblasts from thyroid eye disease patients. BMB Rep. 2021 Feb;54(2):136-141. [Content Brief]
[3]. Kim JW, et al. Exogenous Ganglioside GT1b Enhances Porcine Oocyte Maturation, Including the Cumulus Cell Expansion and Activation of EGFR and ERK1/2 Signaling. Reprod Sci. 2020 Jan;27(1):278-289. [Content Brief]
[4]. Erickson KD, et al. Ganglioside GT1b is a putative host cell receptor for the Merkel cell polyomavirus. J Virol. 2009 Oct;83(19):10275-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ganglioside GT1b (porcine) ammonium Related Classifications
HY-131686A Related Classifications
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