AL-LAD
AL-LAD is a 5-HT2A receptor ligand with rat Ki values of 8.1 nM and 3.4 nM. AL-LAD mediates behavioral responses characteristic of serotonergic psychedelics. AL-LAD induces the head-twitch response in male C57BL/6J mice in an inverted-U-shaped dose-dependent manner. AL-LAD exhibits LSD-like behavioral effects in male C57BL/6J mice.
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- No. CAS: 65527-61-9
- Fòrmula: C22H27N3O
- Peso molecular:349.47
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Almacenamiento:
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
5-HT2A Receptor 8.1 nM (Ki) |
5-HT2A Receptor 3.4 nM (Ki) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6J (male, 6−8 weeks old)[1]
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Dosage:25 µg/kg; 50 µg/kg; 100 µg/kg; 200 µg/kg; 400 µg/kg
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Administration:i.p.; single dose
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Result:Dose-dependently induced HTR with an inverted-U-shaped response; maximal response occurred at 200 μg/kg.
Chemical Information
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No. CAS 65527-61-9
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Peso molecular 349.47
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Fòrmula C22H27N3O
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SMILES
[H][C@@]1(CC2=CNC3=CC=CC4=C23)C4=C[C@H](CN1CC=C)C(N(CC)CC)=O
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Synonyms
6-Allyl-6-nor-LSD
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AL-LAD Related Classifications
HY-W743888 Related Classifications
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Keywords
- AL-LAD
- 65527-61-9
- 6-Allyl-6-nor-LSD
- 5-HT Receptor
- Dopamine Receptor
- Serotonin Receptor
- 5-hydroxytryptamine Receptor
- 5-HT2A receptor
- rat frontal cortex homogenates
- rat
- D1 dopaminergic receptors
- male C57BL/6J mice
- [125I]-R-DOI
- serotonergic psychedelics
- [3H]ketanserin
- head-twitch response
- D2 dopaminergic receptors
- Inhibitor
- inhibitor
- inhibit