OPB-3206
OPB-3206 is a selective matrix metalloproteinase (MMP) inhibitor. OPB-3206 inhibits interstitial collagenase, gelatinase A (MMP-2), gelatinase B (MMP-9) and stromelysin with IC50 values of 7×10-7 M, 5×10-6 M, 5×10-7 M and 2×10-6 M, respectively. OPB-3206 reversibly binds to the zinc-binding region of MMPs, preventing the activation of MMP-9 and reducing extracellular matrix degradation to inhibit tumor lung metastasis. OPB-3206 is promising for research of lung metastasis of osteosarcoma.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 166245-54-1
- Fòrmula: C18H25N3O5
- Peso molecular:363.41
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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MMP-2 5 μM (IC50) |
MMP-9 0.5 μM (IC50) |
Chemical Information
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No. CAS 166245-54-1
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Peso molecular 363.41
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Fòrmula C18H25N3O5
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SMILES
CON1C2=CC=CC=C2C[C@@H](C1=O)NC([C@H](CC(C)C)CC(NO)=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
OPB-3206 Related Classifications
HY-171776 Related Classifications
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