Pentixafor peptide cyclo(dTyr-dOrn(NMe)-R-Nal-G)
Pentixafor peptide cyclo(dTyr-dOrn(NMe)-R-Nal-G) is a peptide that targets CXCR4. Pentixafor peptide cyclo(dTyr-dOrn(NMe)-R-Nal-G) constitutes the peptide moiety of Pentixafor (HY-153549). Pentixafor is a highly selective cyclic pentapeptide ligand targeting the CXCR4 receptor and is suitable for research into radionuclide-drug conjugates (RDCs).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1339959-27-1
- Fòrmula: C36H47N9O6
- Peso molecular:701.82
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Radionuclide-Drug Conjugates (RDCs)
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
CXCR4 |
RDC Peptide |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
6 nM
Compound: 7
|
Displacement of [125I]-CPCR4 from CXCR4 receptor in human Jurkat cells after 2 hrs by gamma counting
Displacement of [125I]-CPCR4 from CXCR4 receptor in human Jurkat cells after 2 hrs by gamma counting
|
[PMID: 21905730] |
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 1339959-27-1
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Peso molecular 701.82
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Fòrmula C36H47N9O6
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Sequence
Cyclo(dTyr-dOrn(NMe)-Arg-Nal-Gly)
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Sequence Shortening
Cyclo(dTyr-dOrn(NMe)-R-Nal-G)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)