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Urelumab

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Based on 1 publication(s) in Google Scholar

Urelumab, a fully human, non-ligand binding, CD137 agonist IgG4 monoclonal antibody, enhances T-cell and natural killer-cell antitumor activity, and may enhance cytotoxic activity of Rituximab (HY-P9913). Urelumab can be used for the research of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL).

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  • Pureza: 99.138%
  • No. CAS: 934823-49-1
  • Peso molecular:145.82 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Urelumab
  • Experimental Validation Results for Urelumab
  • Experimental Validation Results for Urelumab
  • Urelumab Chemical Structure
    Urelumab Chemical Structure
No. CAS: 934823-49-1
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609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Urelumab (HY-P99055, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized 4-1BB/TNFRSF9 Protein, Human can bind Urelumab. The EC50 for this effect is 12.68 ng/mL.

  • Urelumab Chemical Structure
    1/16
  • Urelumab
  • Flow cytometric analysis of 1X106 Jurkat cells with Urelumab (HY-P99055, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized 4-1BB/TNFRSF9 Protein, Human can bind Urelumab. The EC50 for this effect is 12.68 ng/mL.