Y02224
Y02224 is a potent BRD4 inhibitor and exhibits reasonable antiproliferative effect on leukemia cells.Y02224 has the potential for? CRPC research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1853988-48-3
- Fòrmula: C20H17BrN2O4S
- Peso molecular:461.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Actividad biológica
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Chemical Information
- Pureza y Documentación
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Help & FAQs
Actividad biológica
IC50: BRD4[1]
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
2.99 μM
Compound: 85
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Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay
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[PMID: 26731490] |
| HT-29 | IC50 |
12.9 μM
Compound: 85
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Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay
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[PMID: 26731490] |
| MV4-11 | IC50 |
1.3 μM
Compound: 85
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Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay
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[PMID: 26731490] |
Chemical Information
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No. CAS 1853988-48-3
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Peso molecular 461.33
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Fòrmula C20H17BrN2O4S
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SMILES
O=C1C2=C(C3=CC=C2)C(N1CC)=CC=C3NS(C4=C(C=CC(Br)=C4)OC)(=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Y02224 Related Classifications
HY-114902 Related Classifications
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