Map4 - microtubule-associated protein 4 Gene

Also Known as MAP-4; Mtap4; Mtap-4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17758

Summary

Enables microtubule binding activity. Involved in microtubule Cytoskeleton organization. Acts upstream of or within establishment of spindle orientation; microtubule sliding; and mitotic spindle organization. Located in postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; gut; musculature; and trunk mesenchyme. Orthologous to human MAP4 (microtubule associated protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Map4 Products (6)

mRNA Protein Name
NM_001205330.1 NP_001192259.1 microtubule-associated protein 4 isoform 1
NM_001205331.1 NP_001192260.1 microtubule-associated protein 4 isoform 3
NM_001205332.1 NP_001192261.1 microtubule-associated protein 4 isoform 4
NM_001311163.1 NP_001298092.1 microtubule-associated protein 4 isoform 5
NM_001311164.1 NP_001298093.1 microtubule-associated protein 4 isoform 6
NM_008633.4 NP_032659.2 microtubule-associated protein 4 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
21822276 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
26487268 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within establishment of spindle orientation IDA
IDA: Inferred from direct assay
21822276 MGI
involved in microtubule cytoskeleton organization IDA
IDA: Inferred from direct assay
10542369 MGI
acts upstream of or within microtubule sliding IDA
IDA: Inferred from direct assay
21822276 MGI
acts upstream of or within mitotic spindle organization IDA
IDA: Inferred from direct assay
21822276 MGI
Cellular Component GO Annotation Evidence References Source
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-associated protein 4

  • MAP 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (70)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-160623 Rentosertib 99.96% Unkown
HY-100343 GNE-495 Inhibitor 99.49% Unkown
HY-15434 NG25 Inhibitor 98.68% Unkown
HY-19562 PF-06260933 Inhibitor 99.39% Unkown
HY-147141 HS-276 Inhibitor 98.93% Unkown
HY-111754 DMX-5804 Inhibitor 99.83% Unkown
HY-168972 Famlasertib Inhibitor 99.94% Unkown
HY-125012 MAP4K4-IN-3 Inhibitor 99.77% Unkown
HY-138568 HPK1-IN-3 Inhibitor 98.61% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-N3127 Orobol Inhibitor 99.74% Unkown
HY-77251 TAK1/MAP4K2 inhibitor 1 Inhibitor 99.91% Unkown
HY-132290 TGFβRI-IN-3 Inhibitor 98.21% Unkown
HY-138742 HPK1-IN-7 Inhibitor 99.11% Unkown
HY-123714 TL4-12 99.82% Unkown
HY-148061 DB1113 99.86% Unkown
HY-148063 DB0614 96.07% Unkown
HY-W003471 Pyrrolo[2,1-f][1,2,4]triazin-4-amine Inhibitor / Unkown
HY-U00428A GNE 220 hydrochloride Inhibitor 98.22% Unkown
HY-137343 DB-0646 Degrader 98.0% Unkown
HY-156523 TNIK&MAP4K4-IN-1 99.73% Unkown
HY-170443 PF-07265028 Inhibitor 98.04% Unkown
HY-19562A PF-06260933 hydrochloride Inhibitor 99.42% Unkown
HY-U00428 GNE 220 Inhibitor / Unkown
HY-145036 HPK1-IN-10 Inhibitor / Unkown
HY-145037 HPK1-IN-11 Inhibitor / Unkown
HY-145038 HPK1-IN-12 Inhibitor / Unkown
HY-145039 HPK1-IN-13 Inhibitor / Unkown
HY-145040 HPK1-IN-14 Inhibitor / Unkown
HY-145041 HPK1-IN-15 Inhibitor / Unkown
HY-145042 HPK1-IN-16 Inhibitor / Unkown
HY-145044 HPK1-IN-17 Inhibitor / Unkown
HY-145045 HPK1-IN-18 Inhibitor / Unkown
HY-15434A NG25 trihydrochloride Inhibitor / Unkown
HY-101164 MAP4 Antagonist / Unkown
HY-123965 PF-06745013 Inhibitor / Unkown
HY-143868 HPK1-IN-27 Inhibitor / Unkown
HY-143871 HPK1-IN-30 Inhibitor / Unkown
HY-145035 HPK1-IN-9 / Unkown
HY-147141A HS-276 hydrochloride Inhibitor / Unkown
HY-147141B HS-276 formic Inhibitor / Unkown
HY-156509 HPK1-IN-38 Inhibitor / Unkown
HY-162922 MAP4K4-IN-6 Inhibitor / Unkown
HY-169199 BAY-405 Inhibitor / Unkown
HY-179111 HPK1-IN-64 Inhibitor / Unkown
HY-179338 HPK1-IN-65 / Unkown
HY-E70839 KHS1 Recombinant Human Active Protein Kinase / Unkown
HY-E70861 SIK1 Recombinant Human Active Protein Kinase / Unkown
HY-RS08070 MAP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08071 MAP4K1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08072 Map4k1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08073 Map4k1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08074 MAP4K2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08075 Map4k2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08076 Map4k2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08077 MAP4K3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08078 Map4k3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08079 Map4k3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08080 MAP4K4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08081 Map4k4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08082 Map4k4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08083 MAP4K5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08084 Map4k5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08085 Map4k5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W207224 F1386-0303 Inhibitor / Unkown
HY-W402208 MAP4K4-IN-7 Inhibitor / Unkown
HY-159905 HPK1-IN-54 Inhibitor / Unkown
HY-178775 PI4K-IN-3 Inhibitor / Unkown
HY-RS17963 Map4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24434 Map4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map4 NCBI NCBI:4134